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. 2001 May 29;98(13):7629–7634. doi: 10.1073/pnas.121574098

Figure 5.

Figure 5

Lipid content in skin of 10-month-old K5-COX-2 transgenic (B and D, trA and trB) and wt tails (A and C). (A–D) Oil-red staining: note sebaceous gland hyperplasia in transgenic skin (B and D). Ramified sebaceous ducts (B and D), stratum corneum (B), and hair canal (B and D) of transgenic epidermis were stained more intensely than in controls (A and C). [×160 (A and B), ×400 (C and D).] Sebum accumulation on tail surface (E) and shaved neck skin (F) of transgenic (trA and trB) as compared with age-matched wt mice was determined by a sebumeter (SM810; Courage and Khazaka, Cologne, Germany). n = 5; P < 0.05.