Table 1. Kinetics of bone marrow- and DLI-derived T cells in peripheral blood after DLI.
Wks Post-DLI | Total-T | Total BM-T (Recipient BM-T) | Donor DLI-T | ||||||
WT | RagKO | p | WT | RagKO | p | WT | RagKO | p | |
0 | 1.72±0.26 | 1.55±0.14 | 0.094 | 1.72±0.26 (1.05±0.21) | 1.55±0.14 | 0.094 | N/A | N/A | N/A |
2 | 0.55±0.14 | 0.47±0.02 | 0.181 | 0.50±0.14 (0.10±0.02) | 0.10±0.01 | 0.015 | 0.05±0.01 | 0.37±0.02 | 0.002 |
4 | 1.18±0.02 | 0.26±0.01 | 0.0004 | 1.01±0.02 (0.01±0.005) | 0.02±0.002 | 0.001 | 0.17±0.01 | 0.24±0.01 | 0.04 |
Numbers are absolute cell counts of total T cells (Total-T), BM-derived T cells (BM-T) and DLI-derived T cells (DLI-T) in the WBCs (mean±SDs; ×105/mL) at the indicated time points.