Table 3. Stratification analysis of association between GSTP1 genotype and gastric cancer risk.
| Variables | Genotype | Superficialgastritis vs.atrophicgastritis | OR(95% CI) | P value | Superficialgastritis vs.gastriccancer | OR (95% CI) | P value |
| Age/year | |||||||
| ≤60 | Ile/Ile | 317/302 | 1.000 | 238/212 | 1.000 | ||
| Ile/Val | 167/176 | 0.904(0.694–1.177) | 0.454 | 117/104 | 1.001(0.725–1.382) | 0.997 | |
| Val/Val | 10/18 | 0.529(0.24–1.165) | 0.114 | 9/28 | 3.482(1.606–7.547) | 0.002 | |
| >60 | Ile/Ile | 104/128 | 1.000 | 105/119 | 1.000 | ||
| Ile/Val | 80/54 | 1.824(1.185–2.809) | 0.006 | 76/70 | 0.815(0.537–1.238) | 0.337 | |
| Val/Val | 5/5 | 1.232(0.347–4.373) | 0.746 | 5/17 | 2.981(1.063–8.364) | 0.038 | |
| Sex | |||||||
| Male | Ile/Ile | 238/244 | 1.000 | 226/228 | 1.000 | ||
| Ile/Val | 146/136 | 0.909(0.677–1.22) | 0.524 | 138/115 | 0.821(0.603–1.119) | 0.212 | |
| Val/Val | 9/13 | 1.408(0.591–3.356) | 0.44 | 9/30 | 3.297(1.53–7.104) | 0.002 | |
| Female | Ile/Ile | 183/186 | 1.000 | 117/103 | |||
| Ile/Val | 101/94 | 0.921(0.65–1.305) | 0.645 | 55/59 | 1.213(0.771–1.909) | 0.404 | |
| Val/Val | 6/10 | 10.641(0.584–4.609) | 0.347 | 5/15 | 3.402(1.195–9.687) | 0.022 | |
| H. pylori | |||||||
| Negative | Ile/Ile | 311/175 | 1.000 | 253/168 | 1.000 | ||
| Ile/Val | 186/84 | 0.804(0.585–1.106) | 0.180 | 153/92 | 0.887(0.64–1.228) | 0.470 | |
| Val/Val | 10/9 | 1.600(0.638–4.014) | 0.317 | 10/19 | 2.788(1.263–6.153) | 0.011 | |
| Positive | Ile/Ile | 110/255 | 1.000 | 90/163 | 1.000 | ||
| Ile/Val | 61/146 | 1.036(0.713–1.506) | 0.852 | 40/82 | 1.129(0.714–1.784) | 0.603 | |
| Val/Val | 5/14 | 1.210(0.425–3.443) | 0.721 | 4/26 | 3.538(1.196–10.47) | 0.022 | |
| Smoking | |||||||
| Neative | Ile/Ile | 197/233 | 1.000 | 136/69 | 1.000 | ||
| Ile/Val | 117/122 | 0.884(0.644–1.214) | 0.446 | 72/32 | 0.879(0.525–1.473) | 0.625 | |
| Val/Val | 6/13 | 1.828(0.682–4.898) | 0.231 | 5/5 | 1.841(0.505–6.709) | 0.355 | |
| Positive | Ile/Ile | 107/109 | 1.000 | 100/82 | 1.000 | ||
| Ile/Val | 74/70 | 0.921(0.602–1.41) | 0.705 | 67/47 | 0.87(0.539–1.407) | 0.571 | |
| Val/Val | 4/2 | 0.493(0.088–2.77) | 0.422 | 4/12 | 3.638(1.122–11.79) | 0.031 | |
| Alcohols | |||||||
| Negative | Ile/Ile | 231/263 | 1.000 | 170/74 | 1.000 | ||
| Ile/Val | 132/142 | 0.948(0.705–1.275) | 0.725 | 86/32 | 0.836(0.508–1.376) | 0.482 | |
| Val/Val | 9/12 | 1.167(0.483–2.823) | 0.731 | 8/9 | 2.635(0.965–7.197) | 0.059 | |
| Positive | Ile/Ile | 69/77 | 1.000 | 62/49 | 1.000 | ||
| Ile/Val | 52/49 | 0.847(0.509–1.41) | 0.523 | 48/28 | 0.744(0.404–1.371) | 0.343 | |
| Val/Val | 1/3 | 2.657(0.27–26.175) | 0.402 | 1/7 | 9.88(1.173–83.22) | 0.035 |