Table 5. Interaction between GSTP1 Ile/Val polymorphism and H. pylori infection, smoking, and alcohol consumption in gastric cancer.

			superficial gastritis vs gastric cancer
			Ile/Ile	Ile/Val	Val/Val	Ile/Val + Val/Val
H. pylori	(–)	superficial gastritis/gastric cancer	253/168	153/92	10/19	163/111
		OR (95% CI)	1.000	0.906(0.655–1.252)	2.861(1.298–6.306)	1.026(0.752–1.399)
	(+)	superficial gastritis/gastric cancer	90/163	40/82	4/26	44/108
		OR (95% CI)	2.727(1.975–3.767)	3.087(2.018–4.724)	9.789(3.356–28.555)	3.696(2.475–5.521)
				P  = 0.000	P  = 0.000	P  = 0.000
Smoking	(–)	superficial gastritis/gastric cancer	136/69	72/32	5/5	77/37
		OR (95% CI)	1.000	0.876(0.527–1.455)	1.971(0.552–7.04)	0.947(0.582–1.542)
	(+)	superficial gastritis/gastric cancer	100/82	67/47	4/12	71/59
		OR (95% CI)	1.616(1.071–2.439)	1.383(0.862–2.217)	5.913(1.839–19.015)	1.638(1.044–2.571)
				P  = 0.040	P  = 0.003	P  = 0.023
Alcohol	(–)	superficial gastritis/gastric cancer	170/74	86/32	8/9	94/41
		OR (95% CI)	1.000	0.855(0.524–1.394)	2.584(0.96–6.96)	1.002(0.634–1.583)
	(+)	superficial gastritis/gastric cancer	62/49	48/28	1/7	49/35
		OR (95% CI)	1.816(1.142–2.886)	1.34 (0.781–2.3)	16.081(1.944–133.038)	1.641(0.983–2.739)
				P  = 0.028	P  = 0.000	P  = 0.027

P values were adjusted for age and sex.