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. 2012 Oct 15;7(10):e45226. doi: 10.1371/journal.pone.0045226

Figure 4. Examples of the effect of parameter addition or removal.

Figure 4

A. Truncated SCRIT vectors containing only data collected in glu+ conditions demonstrate hierarchical clustering where direct mitochondrial toxicants oligomycin, antimicynA, rotenone, and valinomacin separated into different clusters. B. Six parameters were used for the statin SCRIT vector formation to detect changes in cell response induced by individual statins. Glu+ - glucose-containing medium, Glu− - glucose-free medium, 1 – TMRM integral, 2 – Hoechst33342 mean 3 – viability, 4 – TMRM maximum pixel, 5 – nuclear area, 6 – nuclear circularity. Arrow points to the TMRM max pixel dose response part of the SCRIT vector.