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. 2012 Oct 15;7(10):e47115. doi: 10.1371/journal.pone.0047115

Figure 5. The effects of different treatments on cell cycle, proliferation index and apoptosis index by flow cytometry analysis of H22 cells.

Figure 5

(A) Quantification of cell cycle distribution and proliferation index of H22 cells. Percentage of cells in G0–G1 in the GC/5-FU,CS/5-FU and 5-FU groups was higher than in the control and GC groups, and the proliferation index decreased significantly in the other three groups (P<0.01). (B) Quantification of apoptosis of H22 in different treatment groups. The percentage of apoptotic cells in the GC/5-FU,CS/5-FU and 5-FU groups was significantly higher than in the control and GC groups (P<0.01). The percentage of apoptotic cells in the GC/5-FU group was also higher than in the 5-FU (P<0.01) and CS/5-FU groups (P<0.05). **P<0.01 compared with control or GC group; ##P<0.01 compared with the 5-FU group; ▴P<0.05 compared with the CS/5-FU group.