Table 1.

Associations between calpastatin, calpain-1 and calpain-2 protein expression and various clinicopathological variables. The frequency of observed clinicopathological variables is noted next to the variable subgroup. The P-values are resultant from Pearson chi-square test of association (χ²) or Fisher's exact test in a 2 × 2 table if a cell count was less than 5 (indicated by *). Significant P-values are indicated by bold font

Variable	Calpastatin			Calpain-1			Calpain-2
	Low	High	P-value	Low	High	P-value	Low	High	P-value
Pathology
Serous (n = 91)	11	56	<0.001	5	62	0.003	13	55	<0.001
Mucinous (n = 11)	5	3		0	8		4	4
Endometrioid (n = 29)	9	15		7	18		9	15
Clear cell (n = 20)	11	6		7	10		14	3
Others (n = 3)	2	0		0	1		0	1
Grade
1 (n = 19)	5	10	0.556	2	13	0.925	4	10	0.313
2 (n = 22)	3	12		2	12		3	13
3 (n = 113)	30	58		15	74		33	55
Debulking surgery
Optimal (n = 90)	27	44	0.096	13	57	0.378	27	42	0.154
Suboptimal (n = 64)	11	36		6	42		13	36
Stage
I (n = 42)	16	19	0.105	8	27	0.637	17	17	0.103
II (n = 20)	3	11		2	12		4	10
III (n = 71)	17	37		7	46		16	38
IV (n = 21)	2	13		2	14		3	13
Chemotherapy
Carboplatin monotherapy (n = 60)	20	30	0.103	10	41	0.405	19	30	0.315
Carboplatin combination (n = 88)	17	49		9	56		20	47
Platinum sensitivity
Sensitive (n = 104)	27	54	0.698	15	66	0.419*	32	47	0.031
Resistant (n = 50)	11	26		4	33		8	31
Progression-free status
progression-free (n = 65)	22	32	0.064	10	45	0.646	23	29	0.053
progressive disease (n = 85)	15	46		9	51		17	46
Survival status
Living (n = 75)	19	43	0.703	9	54	0.566	27	34	0.014
Deceased (n = 79)	19	37		10	45		13	44