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. Author manuscript; available in PMC: 2013 Nov 10.
Published in final edited form as: J Mol Biol. 2012 Sep 11;423(5):766–781. doi: 10.1016/j.jmb.2012.08.027

Figure 1. The STAR family of RNA-binding proteins.

Figure 1

Domain structure of QkI and constructs used in this study. The Qua1, KH and Qua2 subdomains are shaded (top). Sequence alignment of the Qua1 domain of representative members of the STAR/GSG protein family (bottom). Identical conserved residues are highlighted in dark grey, similar residues in light grey. The secondary structure of the Quaking Qua1 domain is shown above. Members of the Quaking subfamily feature a 3-residue insertion between the two large helices which form an additional short helix, instead of a simple turn, that is not present in the Qua1 structures of GLD-1 and Sam68.