Fig. 5. Significantly altered miR-200a and miR-200c were detected in the cortex and striatum of N171-82Q HD mice by quantitative RT-PCR.
MiR-200a levels were significantly upregulated in the cortex (a) and striatum (b) of 12-week-old HD mice; miR-200c levels were significantly upregulated in the cortex (c) and striatum (d) of 12-week-old HD mice. Bars represent Mean and STD, n= 5–6 mice in each group. *p<0.05 vs the levels of age-matched littermate controls by Student’s t-tests.