. Author manuscript; available in PMC: 2013 Oct 1.

Published in final edited form as: J Crit Care. 2012 May 15;27(5):496–504. doi: 10.1016/j.jcrc.2012.02.002

Table 2.

Acute kidney injury definition.

	Creatinine (over 48 hours) & renal replacement therapy criteria	Modified urine output criteria^a

AKI	1) Acute increase in serum creatinine of ≥0.3 mg/dL or to ≥150% of baseline, OR	<0.5mL/kg/h for 24 hours
	2) Creatinine ≥4.0 mg/dL with an acute increase of ≥0.5 mg/dL, OR
	3) Need for renal replacement therapy
Stage 1	Acute increase in serum creatinine of ≥0.3mg/dL or to 150% to 200% of baseline	Not applicable^a
Stage 2	Acute increase in serum creatinine to >200% to 300% of baseline	<0.5mL/kg/h and ≥0.3mL/kg/h for 24 hours
Stage 3	1) Acute increase in serum creatinine to >300% of baseline, OR	<0.3mL/kg/h for 24 hours
	2) Creatinine ≥4.0 mg/dL with an acute increase of ≥0.5 mg/dL, OR
	3) Need for renal replacement therapy

Cr, RRT, and stage 3 urine output criteria are taken from the Acute Kidney Injury Network (AKIN) consensus criteria (17).

Given the lack of 6- or 12-hour urine output data, urine output criteria for both AKI and stage 2 are modified to use 24-hour data (AKIN criteria are <0.5mL/kg/h for 6 hours (AKI) and <0.5mg/kg/h for 12 hours (stage 2)). Urine output criterion for stage 1 is not used in this definition (AKIN criterion is <0.5 mL/kg/h for 6 hours).