Table 3.
Multivariable model for AKI risk (n=391a).
| Standardizedc AKI risk (95% CI) | Standardizedc risk difference (95% CI) | Adjustedd odds ratio (95% CI) for AKI | pe | |
|---|---|---|---|---|
|
| ||||
| Race | ||||
| African American | 0.43 (0.36,0.50) | 0.11 (0.01,0.22) | 1.83 (1.04,3.24) | 0.036 |
| Non-African American | 0.32 (0.25,0.38) | |||
| Diabetes mellitus | ||||
| Present | 0.58 (0.39,0.77) | 0.22 (0.03,0.41) | 3.01 (1.15,7.91) | 0.025 |
| Absent | 0.36 (0.32,0.41) | |||
| AIS score abdomen | ||||
| ≥4 | 0.63 (0.49,0.78) | 0.30 (0.15,0.46) | 4.45 (2.01,9.85) | <0.001 |
| ≤3 | 0.33 (0.28,0.38) | |||
| BMI category (kg/m2) | ||||
| Underweight (<18.5)a | - | - | - | |
| Normal (18.5–24.9) | 0.26 (0.19,0.32) | Ref | Ref | - |
| Overweight (25.0–29.9) | 0.35 (0.27,0.42) | 0.09 (–0.01,0.19) | 1.65 (0.93,2.92) | 0.086 |
| Obese (≥30.0) | 0.57 (0.48,0.67) | 0.32 (0.20,0.43) | 4.72 (2.59,8.61) | <0.001 |
|
| ||||
| Unmatched PRBC, unitsb | 1.13 (1.03,1.24) per 1 unit | 0.007 | ||
| 0 | 0.34 (0.29,0.39) | - | ||
| 3 | 0.41 (0.36,0.46) | - | ||
| 6 | 0.49 0.39,0.58) | - | ||
| 9 | 0.56 (0.42,0.71) | - | ||
All independently associated variables shown in table. Categorical variables are above, continuous variables below, the dashed line.
a
No underweight subjects developed AKI, resulting in their exclusion from the multivariable model when adjusting for BMI category.
b
Total amount during resuscitation prior to ICU admission.
c
Using post-estimation marginal standardization (see methods).
d
Associations also adjusted for age, hypertension, trauma mechanism, AIS score for head, need for surgery prior to ICU admission, and liters of crystalloid and cross-matched PRBCs administered during resuscitation.
e
Wald test for odds ratio by multivariable logistic regression.