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. Author manuscript; available in PMC: 2013 Oct 12.
Published in final edited form as: Mol Cell. 2012 Aug 30;48(1):75–86. doi: 10.1016/j.molcel.2012.07.034

Figure 1. ATPase cycle of the myosin VI motor.

Figure 1

The different structural states that the myosin VI motor adopts along the ATP hydrolysis cycle are indicated with detached states on the left (Post-rigor, 2VAS and Pre-powerstroke (PPS), 4ANJ) and actin-binding states on the right (PPS-4ANJ and Rigor, 2BKH). The motor is composed of important connectors (SwII, orange – relay, yellow – SH1 helix, red) and four subdomains (Nter, grey – U50, blue – L50, white – converter, green). Insert-2 and its bound Ca2+-calmodulin are in purple and pink.