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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: Neuroimage. 2012 Aug 10;63(3):1532–1541. doi: 10.1016/j.neuroimage.2012.08.007

Table 3.

The accuracy (ratio) and precision (SD) of various scaling methods to estimate plasma area-under-the-curve (AUC) and distribution volume (VT) compared to arterial input function

Scaling method AUC
(ratio ± SD)		 VT
(ratio ± SD)
Two blood samples 0.99 ± 0.11 1.00 ± 0.05
Weight 1.04 ± 0.22 1.01 ± 0.32
Lean Body Mass
    James 1.03 ± 0.19 1.00 ± 0.25
    Hume 1.03 ± 0.19 1.00 ± 0.26
Body Surface Area
    Du Bois 1.03 ± 0.18 1.00 ± 0.27
    Boyd 1.03 ± 0.19 1.00 ± 0.28
    Gehan 1.03 ± 0.19 1.00 ± 0.28
    Haycock 1.03 ± 0.19 1.00 ± 0.28
    Mosteller 1.03 ± 0.19 1.00 ± 0.27
    Tikuisis 1.03 ± 0.19 1.00 ± 0.27
    Yu 1.03 ± 0.18 1.00 ± 0.27