. Author manuscript; available in PMC: 2013 Nov 1.

Published in final edited form as: Hum Genet. 2012 Jul 3;131(11):1751–1759. doi: 10.1007/s00439-012-1195-x

Table 4.

Top five terms in UniProt tissue expression chart by karyotype

Karyotype	UniProt KB term	No. of genes	P value^*
Euploid	Fetal brain cortex	41	6.34E–18
	Cajal–Retzius cell^a	35	2.83E–14
	Epithelium	154	1.23E–13
	B-cell lymphoma	24	5.86E–10
	Skin	102	1.71E–07
Trisomy 21	Epithelium	342	1.21E–35
	Placenta	377	6.06E–27
	Fetal brain cortex	63	4.24E–22
	Cajal–Retzius cell^a	59	3.20E–21
	Skin	216	1.26E–16
Trisomy 18	Epithelium	224	1.11E–23
	Fetal brain cortex	50	1.37E–20
	Cajal–Retzius cell^a	44	2.39E–17
	Skin	140	2.05E–10
	Placenta	220	2.24E–10

Benjamini–Hochberg corrected modified Fisher exact P value

See Supplemental Table 5 for genes expressed by Cajal–Retzius cells that were detected in the euploid, trisomy 21 and trisomy 18 AF transcriptomes