Table 1. List of 23 candidate gene and GWAS-identified SNPs genotyped in NHANES.
For each SNP (denoted by rs number), we list the chromosomal and genomic location (base-pair), the putative function of the SNP (based on SNP location), and the nearest gene of interest.
| SNP | Chr. | Build 37 location (bp) | Coded Allele | Function | Gene of Interest |
|---|---|---|---|---|---|
| rs11206510 | 1 | 55495789 | C | Intergenic | PCSK9 |
| rs1748195 | 1 | 63049343 | C | Intronic | ANGPTL3 |
| rs693 | 2 | 21231945 | T | Synonymous | APOB |
| rs754523 | 2 | 21311441 | C | Intergenic | APOB |
| rs780094 | 2 | 27740987 | A | Intronic | GCKR |
| rs12654264 | 5 | 74648353 | A | Intronic | HMGCR |
| rs1501908 | 5 | 156397919 | C | Intergenic | TIMD4 |
| rs2197089 | 8 | 19826123 | C | Downstream | LPL |
| rs2954029 | 8 | 126560154 | A | Intergenic | TRIB1 |
| rs4149268 | 9 | 107647220 | A | Intronic | ABCA1 |
| rs3890182 | 9 | 107647405 | A | Intronic | ABCA1 |
| rs1883025 | 9 | 107664051 | G | Intronic | ABCA1 |
| rs174547 | 11 | 61570533 | C | Intronic | FADS1 |
| rs3135506 | 11 | 116662157 | C | Non- synonymous | APOA1/C3/A4/A5 gene cluster |
| rs2338104 | 12 | 109894918 | C | Intronic | MMAB-MVK |
| rs4775041 | 15 | 58674445 | C | Intergenic | LIPC |
| rs9989419 | 16 | 56984889 | A | Upstream | CETP |
| rs3764261 | 16 | 56993074 | G | Upstream | CETP |
| rs2271293 | 16 | 67901820 | A | Intronic | LCAT |
| rs2156552 | 18 | 47181418 | A | Intergenic | LIPG |
| rs2967605 | 19 | 8469488 | G | Downstream | ANGPTL4 |
| rs6102059 | 20 | 39228784 | C | Intergenic | MAFB |
| rs7679 | 20 | 44576252 | C | Downstream | PLTP |