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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Free Radic Biol Med. 2012 Aug 25;53(9):1738–1747. doi: 10.1016/j.freeradbiomed.2012.08.576

Fig. 4. Effects of hydralazine (HDZ) on pulmonary artery SMC growth.

Fig. 4

(A) Cell lysates from FBS-stimulated pulmonary artery SMCs (control) were treated in vitro with HDZ before derivatization with DNPH and subsequent immunoblotting to demonstrate that HDZ interacts with protein carbonyl groups and competes with DNPH. The bar graph represents means ± SEM (n = 3 – 4). *, P<0.05 vs. untreated control. (B) Growth-arrested bovine pulmonary artery SMCs were pre-treated for 30 min with HDZ and then treated with 10% FBS for 3 days. Cell growth was monitored by XTT assay. The bar graph represents means ± SEM (n = 8).*, P<0.05 vs. untreated control; a, P<0.05 vs. FBS.