Table 3.
Haplotype frequencies and association results of six SNPs with red blood cell count (RBC) and mean corpuscular volume (MCV)
|
Haplotypes |
Tagging SNPs for ABO gene region |
Haplotype frequency |
RBC |
MCV |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs2073823 | rs8176720 | rs8176717 | rs687289 | rs8176681 | rs495828 | beta ± se | p | beta ± se | p | ||
| Hap 1 |
G |
T |
G |
G |
C |
G |
0.297 |
0.008 ± 0.007 |
0.249 |
0.064 ± 0.106 |
0.544 |
| Hap 2 |
G |
T |
G |
A |
T |
T |
0.261 |
−0.030 ± 0.007 |
2.63 × 10-5 |
0.064 ± 0.111 |
0.563 |
| Hap 3 |
G |
C |
T |
G |
T |
G |
0.214 |
−0.013 ± 0.008 |
0.103 |
0.363 ± 0.118 |
2.09 × 10-3 |
| Hap 4 |
A |
C |
G |
A |
T |
G |
0.208 |
0.036 ± 0.008 |
4.27 × 10-6 |
−0.512 ± 0.119 |
1.81 × 10-5 |
| Hap 5 |
G |
T |
G |
G |
T |
G |
0.012 |
NA |
NA |
NA |
NA |
| Hap 6 | A | C | G | A | C | G | 0.007 | NA | NA | NA | NA |