Table 2.
Gene ontology analysis of genes affected by combined genistein and vorinostat treatment using DAVID knowledgebase (columns 1–4) and ingenuity knowledgebase (columns 5–7)
| GO Term | Biological Process | Count | p-value | IPA Biological Function | Count | p-value |
|---|---|---|---|---|---|---|
| GO:0006281 |
DNA repair |
45 |
1.03E-13 |
DNA Replication, Recombination, and Repair |
39 |
7.18E-12 |
| GO:0008219 |
Cell Death |
48 |
2.73E-03 |
Cell Death |
122 |
1.95E-10 |
| GO:0022403 |
Cell Cycle |
57 |
1.63E-14 |
Cell Cycle |
105 |
2.70E-09 |
| GO:0006915 |
Apoptosis |
43 |
1.37E-03 |
Apoptosis |
149 |
1.13E-07 |
| GO:0000075 |
Cell Cycle Checkpoint |
17 |
1.45E-06 |
DNA checkpoint control |
13 |
1.90E-06 |
| GO:0006325 | Chromatin Organization | 28 | 7.01E-03 | Binding Of Chromatin | 5 | 1.69E-03 |