Table 2.
Animal models and number of mice
| Model | Cell line/strain |
Number of cohorts |
Number of mice |
||
|---|---|---|---|---|---|
| Control | Treatment | Control | Treated | ||
| 1 |
BT474 in SCID Nude Beige |
2 |
2 |
22 |
22 |
| 2 |
HCT116 in Nu/Nu |
5 |
8 |
54 |
86 |
| 3 |
PC3 in Nu/Nu |
2 |
2 |
24 |
24 |
| 4 |
FaDu in CB17 SCID |
1 |
1 |
10 |
10 |
| 5 |
H292 in CB17 SCID |
1 |
1 |
10 |
10 |
| 6 |
H596 in huHGF transgenic |
1 |
3 |
11 |
33 |
| 7 |
537-Mel in Nu/Nu |
2 |
4 |
17 |
31 |
| 8 |
A2058 in Nu/Nu |
4 |
10 |
39 |
99 |
| 9 |
A375 in Nu/Nu |
4 |
7 |
35 |
64 |
| 10 |
Colo205 in Nu/Nu |
1 |
1 |
12 |
12 |
| 11 |
H2122 in Nu/Nu |
1 |
3 |
10 |
30 |
| |
Subtotal |
24 |
42 |
244 |
421 |
| Total | 66 | 665 | |||