Table 7.
Changes (nanomole percent by weight composition) in rat brain phosphatidylserine molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)
| Molecular weight | Molecular species | Diacyl species | PBS | PPA |
|---|---|---|---|---|
| 760 |
D34:1 |
16:0/18:1 |
0.90 ± 0.10 |
1.10 ± 0.21 |
| 790 |
D36:0 |
18:0/18:0 |
1.59 ± 0.41 |
1.65 ± 0.11 |
| 788 |
D36:1 |
18:0/18:1 |
18.10 ± 0.53 |
21.62 ± 0.63* |
| 786 |
D36:2 |
18:0/18:2 |
2.36 ± 0.34 |
2.55 ± 0.17 |
| 816 |
D38:1 |
18:0/20:1 |
1.00 ± 0.15 |
1.22 ± 0.19 |
| 810 |
D38:4 |
18:0/20:4 |
4.18 ± 0.07 |
4.46 ± 0.12 |
| 840 |
D40:3 |
18:0/22:3 |
1.19 ± 0.23 |
1.20 ± 0.17 |
| 838 |
D40:4 |
18:0/22:4 |
4.67 ± 0.17 |
3.63 ± 0.14* |
| 836 |
D40:5 |
18:0/22:5 |
6.40 ± 0.30 |
6.91 ± 0.43 |
| 834 |
D40:6 |
18:0/22:6 |
58.39 ± 0.98 |
54.49 ± 1.05* |
| 832 |
D40:7 |
18:1/22:6 |
1.22 ± 0.08 |
1.17 ± 0.12 |
|
Total% |
|
|
100 |
100 |
|
∑ Saturates |
|
|
1.59 ± 0.15 |
1.65 ± 0.11 |
|
∑ Monounsat |
|
|
19.99 ± 0.39 |
23.93 ± 0.66* |
| ∑ Polyunsat | 78.41 ± 0.58 | 74.45 ± 0.55* |
Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. D represents diacyl species. Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution; polyunsat, polyunsaturated fatty acids; PPA, propionic acid. Phosphatidylserine molecular species were identified using neutral loss scan of 87 D in ESI negative mode. The lipid components in the table are arranged based on the molecular species composition.