Table 1.
Examples of C-GATE
| Species * | Type * | Family | Subfamily | Regulatory effect * | Comments * | Gene * | Gene regulatory networks | Environment response? | Date of publication * | Reference (1) * | Reference (2) |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Latin name |
LTR, LINE, SINE, DNA |
TE family |
TE sub-family |
How does the TE impact the gene? |
A clear summary of the publication and/or details on the exaptation event. |
Gene with the TE exaptation |
Is the TE or gene part of a regulatory network? |
Is the exaptation a response to environment changes? |
|
Reference with a link to the journal |
Second reference if necessary |
|
Homo sapiens |
LTR |
ERV-1 |
HERV-9 |
Alternative promoter |
12% of NAIP total expression in testis is due to a LTR9. |
NAIP |
|
|
2007 |
Romanish et al. (2007) PloS Genetics [11] |
|
| Homo sapiens | LTR | ERV-3 | Mer74C | Primary promoter | Bioinformatic analysis of human and mouse RefSeq UTRs. CA1 is transcribed through two promoters one of which is a LTR copy, present in both human and mouse that confers erythroid specific expression in both species. Chimeras were confirmed through bibliography or RT PCR. Coordinates are from hg18. | CA1 | 2003 | Van de Lagemaat et al. (2003) Trends Genet [18] | Piriyapongsa et al. (2007) BMC Genomics [19] |
* Mandatory field.
Note that columns containing coordinates of the TE, its position relative to the gene and any influence on phenotype have been omitted for clarity but are present in C-GATE.