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. 2012 Jul 30;13:348. doi: 10.1186/1471-2164-13-348

Table 2.

Gene set analysis using Kyoto encyclopedia of genes and genomes (KEGG) pathways

A
 
 
 
 
 
Function KEGG pathway cDNA HU-6800 U133 U95
Cell cycle & DNA replication
 
 
 
 
 
Cell cycle
0.019
0.019
< 0.001
< 0.001
 
DNA replication
0.001
0.125
0.003
0.001
 
Base excision repair
0.003
0.003
0.002
0.003
Cell junction
 
 
 
 
 
Adherens junction
< 0.001
< 0.001
< 0.001
0.001
 
Tight junction
0.004
0.003
0.002
0.006
 
Gap junction
0.011
0.007
0.015
0.014
 
 
 
 
 
 
Cell adhesion molecules
 
 
 
 
 
Focal adhesion
0.016
0.315
0.014
0.015
 
Cell adhesion molecules
0.007
0.007
0.017
0.005
 
Regulation of actin cytoskeleton
0.013
0.013
0.001
< 0.001
B
 
cDNA
HU-6800
U133
U95
Molecular pathway
 
 
 
 
 
Integrin signaling pathway
< 0.001
0.004
0.004
0.001
 
VEGF signaling pathway
0.003
< 0.001
< 0.001
< 0.001
 
Phosphatidylinositol signaling
0.009
0.009
0.006
0.003
 
Wnt signaling pathway
0.004
0.524
< 0.001
< 0.001
 
Jak-STAT signaling pathway
0.034
0.034
< 0.001
0.003
 
MAPK signaling pathway
0.017
0.017
0.002
0.003
 
ErbB signaling pathway
0.014
0.005
0.021
0.014
  p53 signaling pathway 0.035 0.034 0.016 0.006

Adjusted p-value using using Benjamini and Hochberg method as represented in four microarray platforms (significance cutoff is adjusted p-value < 0.01).