Table 2.
A |
|
|
|
|
|
---|---|---|---|---|---|
Function | KEGG pathway | cDNA | HU-6800 | U133 | U95 |
Cell cycle & DNA replication |
|
|
|
|
|
|
Cell cycle |
0.019 |
0.019 |
< 0.001 |
< 0.001 |
|
DNA replication |
0.001 |
0.125 |
0.003 |
0.001 |
|
Base excision repair |
0.003 |
0.003 |
0.002 |
0.003 |
Cell junction |
|
|
|
|
|
|
Adherens junction |
< 0.001 |
< 0.001 |
< 0.001 |
0.001 |
|
Tight junction |
0.004 |
0.003 |
0.002 |
0.006 |
|
Gap junction |
0.011 |
0.007 |
0.015 |
0.014 |
|
|
|
|
|
|
Cell adhesion molecules |
|
|
|
|
|
|
Focal adhesion |
0.016 |
0.315 |
0.014 |
0.015 |
|
Cell adhesion molecules |
0.007 |
0.007 |
0.017 |
0.005 |
|
Regulation of actin cytoskeleton |
0.013 |
0.013 |
0.001 |
< 0.001 |
B |
|
cDNA |
HU-6800 |
U133 |
U95 |
Molecular pathway |
|
|
|
|
|
|
Integrin signaling pathway |
< 0.001 |
0.004 |
0.004 |
0.001 |
|
VEGF signaling pathway |
0.003 |
< 0.001 |
< 0.001 |
< 0.001 |
|
Phosphatidylinositol signaling |
0.009 |
0.009 |
0.006 |
0.003 |
|
Wnt signaling pathway |
0.004 |
0.524 |
< 0.001 |
< 0.001 |
|
Jak-STAT signaling pathway |
0.034 |
0.034 |
< 0.001 |
0.003 |
|
MAPK signaling pathway |
0.017 |
0.017 |
0.002 |
0.003 |
|
ErbB signaling pathway |
0.014 |
0.005 |
0.021 |
0.014 |
p53 signaling pathway | 0.035 | 0.034 | 0.016 | 0.006 |
Adjusted p-value using using Benjamini and Hochberg method as represented in four microarray platforms (significance cutoff is adjusted p-value < 0.01).