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. Author manuscript; available in PMC: 2012 Oct 18.
Published in final edited form as: Curr Mol Med. 2012 Feb;12(2):206–217. doi: 10.2174/156652412798889045

Figure 4. Effect of delapril on excitation-contraction coupling proteins.

Figure 4

Top: Representative Western blot for LTCC: L-type Ca2+ channel; NCX: Na+/Ca2+ exchanger; RyR: ryanodine receptor 2; P-RyR: phosphorylated ryanodine receptor; SERCA2a: SR Ca2+ ATPase 2a; Total PLB: total phospholamban; PS16-PLB: PLB phosphorylated by PKA at Serine 16; PT17-PLB: phospholamban phosphorylated by CaMKII at the threonine-17 site. A. Mean ± S.E.M. of LTCC, NCX, RyR and P-RyR/RyR protein expression levels in Sham (n=5), MI (n=6), and MI-D mice (n=6). B. Mean ± S.E.M. of SERCA2a, Total PLB, PS16-PLB and PT17-PLB protein expression levels. C. Mean ± S.E.M. of PS16-PLB/PLB, PT17-PLB/PLB and PLB/SERCA2a ratio. Molecular Weight in kDa. *P<0.05 in comparison with Sham mice. †P<0.05 in comparison with MI mice.