. Author manuscript; available in PMC: 2012 Oct 18.

Published in final edited form as: Curr Mol Med. 2012 Feb;12(2):206–217. doi: 10.2174/156652412798889045

Table 1.

Morphological and functional parameters in vivo

	Sham	MI	% Sham	MI-D	% Sham
*Weight*	n=9	n = 9		n = 18
BW (g)	39.2 ± 2.6	38.9 ± 3.0		39.7 ± 2.5
HW/BW (mg/g)	5.4 ± 0.3	7.6 ± 0.4^*	+41	6.3 ± 0.3 ^*^†	+17
*Echocardiography*	n = 18	n = 18		n = 21
Systole
PWT (mm.10⁻¹)	14.9 ± 0.6	11.5 ± 1.1^*	−23	12.6 ± 1.0	−15
LVEsD (mm.10⁻¹)	19.4 ± 0.6	56.4 ± 3.2^*	+191	44.9 ± 1.4^*^†	+131
Diastole
PWT (mm.10⁻¹)	7.58 ± 0.27	6.33 ± 0.29 ^*	−16	6.34 ± 0.42 ^*	−16
LVEdD (mm.10⁻¹)	40.7 ± 1.0	65.0 ± 2.7^*	+60	54.4 ± 1.4^*^†	+34
SF (%)	52 ± 1	13 ± 2^*	−75	17 ± 1^*^†	−67
Haemodynamic	n = 14	n = 14		n = 15
Pressure
LVEsP (mmHg)	83 ± 3	67 ± 3^*	−19	65 ± 4^*	−22
LVEdP (mmHg)	0 ± 3	7 ± 2^*		−3 ± 1 ^†
Max dP/dt (mmHg/s)	5223 ± 551	4129 ± 198 ^*	−21	4518 ± 380	−13
Min dP/dt (mmHg/s)	−3934 ± 460	−3037 ± 157 ^*	−23	−3401 ± 226	−14
EDV (μl)	23 ± 1	29 ± 1^*	+21	27 ± 1^*^†	+17
SV (μl)	17 ± 1	26 ± 1^*	+53	23 ± 1^*^†	+35

BW: body weight; HW: heart weight; PWT: posterior wall thickness; LVEsD: LV end-systolic diameter; LVEdD: LV end-diastolic diameter; SF: shortening fraction; LVEsP: LV end diastolic pressure; LVEsP: LV End systolic pressure; Max dP/dt: maximum rate of increase in pressure during contraction (positive slope); Min dP/dt: Minimum rate of decrease in pressure during relaxation (negative slope); EDV: end-disatolic volume; SV: systolic volume. Values given are means ± S.E.M.;

P<0.05 MI compared to Sham.

^†

P<0.05 MI-D compared to MI.