Table 1.
Compartmentalization analysis between blood and genital tract
| ID | TP | Test | P-value | Comp | CMV |
|---|---|---|---|---|---|
| L7 | TP1 | SM | 0 | Yes | nd |
| Fst | 0 | ||||
| TP2 | SM | 0 | Yes | 3.97 | |
| Fst | 0.02 | ||||
| TP3 | SM | 0.01 | Yes | 3.02 | |
| Fst | 0.01 | ||||
| TP4 | SM | 0.79 | No | nd | |
| Fst | 0.8 | ||||
|
| |||||
| X3 | TP1 | SM | 0.98 | No | 3.5 |
| Fst | 0.71 | ||||
| TP2 | SM | 0.72 | No | nd | |
| Fst | 0.33 | ||||
| TP3 | SM | 0.58 | No | nd | |
| Fst | 0.72 | ||||
|
| |||||
| P9 | TP1 | SM | 0 | Yes | nd |
| Fst | 0 | ||||
| TP2 | SM | 1 | No | nd | |
| Fst | 0.97 | ||||
| TP3 | SM | 0 | Yes | 6.81 | |
| Fst | 0 | ||||
| TP4 | S-M | 0 | Yes | 4.45 | |
| F_st | 0 | ||||
|
| |||||
| L3 | TP1 | SM | 0.03 | No | nd |
| Fst | 0.47 | ||||
| TP2 | SM | 0.09 | No | 4.13 | |
| Fst | 0.5 | ||||
| TP3 | SM | 0 | Yes | 4.24 | |
| Fst | 0 | ||||
ID: subject identification number, TP: time point;
Test performed to determine presence of compartmentalization between HIV-1 populations in blood and seminal plasma: SM: Slatkin-Maddison, Fst: Wright-s measure of population subdivision with relatives p-values
Samples is defined as compartmentalized (Comp) if both tests show a p-value <0.05
CMV: Levels of cytomegalovirus in semen are reported as Log10 copies/ml, nd: not detectable