Table 3.
Ingenuity Pathway Analysis of the 22 genes showing significant alterations in adrenergic-deficient E10.5 mouse hearts (from Table 1)
| Top Biological Functions | |
|---|---|
| P Value Range | |
| Diseases and Disorders | |
| Developmental disorder | 5.65E-04-4.93E-02 |
| Endocrine System disorders | 5.65E-04-4.02E-02 |
| Reproductive system dsease | 5.65E-04-3.49E-02 |
| Cancer | 1.26E-03-3.89E-02 |
| Cardiovascular disease | 1.36E-03-4.02E-02 |
| Molecular and Cellular Function | |
| Carbohydrate metabolism | 1.36E-03-8.16E-03 |
| Cell cycle | 1.36E-03-4.15E-02 |
| Cell-to-cell signaling and interaction | 1.36E-03-4.02E-02 |
| Cellular assembly and organization | 1.36E-03-4.15E-02 |
| Cellular development | 1.36E-03-4.41E-02 |
| Physiological System and Development and Function | |
| Behavior | 1.36E-03-2.30E-02 |
| Cell-mediated Immune Response | 1.36E-03-8.16E-03 |
| Connective Tissue Development and Function | 1.36E-03-4.28E-02 |
| Endocrine System Development and Function | 1.36E-03-3.23E-02 |
| Hematological System Development and Function | 1.36E-03-4.41E-02 |
| Top Canonical Pathways | |
| P Value | |
| Retinol metabolism | 1.62E-03 |
| Eicosanoid signaling | 2.8E-03 |
| IL-15 production | 3.62E-02 |
| O-glycan biosynthesis | 4.15E-02 |
| MIF-mediated glucocorticoid regulation | 4.41E-02 |