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PANTHER (Protein Analysis Through Evolutionary Relationships) biological function representation of 67 nonredundant proteins that differed significantly with age-associated estrogen (E2) deficiency identified by isobaric tags for relative and absolute quantification (iTRAQ) 8plex analyses (instantaneous false discovery rate <5.0% and unused score >1.3). Data based on adult (n = 5), aged ovary-intact (n = 6), and aged ovariectomized (OVX, n = 5) female F344 rats.
