Table 3.
Myocardial function during heart perfusion with various substrates
| Glucose | Lactate | Pyruvate | Hexanoate | |
|---|---|---|---|---|
| Heart rate, beats/min | 274 ± 14 | 282 ± 15 | 280 ± 7 | 270 ± 7 |
| LVDP, mmHg | 129 ± 6 | 130 ± 6 | 130 ± 6 | 136 ± 6 |
| RPP, mmHg/min | 35,602 ± 2,741 | 36,846 ± 2,764 | 36,225 ± 1,423 | 36,618 ± 1,654 |
| CF, ml · min−1 · g wet wt−1 | 12.1 ± 0.9 | 12.3 ± 0.6 | 12.0 ± 0.7 | 13.5 ± 0.6* |
| O2 consumption, μmol · min−1 · g wet wt−1 | 8.3 ± 0.9 | 8.9 ± 0.8 | 9.0 ± 0.6 | 9.8 ± 0.6* |
| Metabolic efficiency, mmHg/μmol | 4,098 ± 503 | 3,876 ± 390 | 3,953 ± 328 | 3,534 ± 275 |
Values are means ± SE. The number of experiments was 10 per group.
*
P < 0.05 indicates a significant difference.