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Representative phrenic neurograms depicting experimental protocols in rats treated post-AIH. Spinal injection post-AIH (<5 min) of vehicle (12 μl; A), vehicle control (no AIH; B), MEK inhibitor (U0126, 12 μl; C), and U0126 control (no AIH; D) treatments are shown. Post-AIH U0126 attenuated pLTF at 60 and 90 min compared with vehicle-treated rats exposed to AIH.
