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Rapid hyperemic (ΔFBF) and vasodilator (ΔFVC) responses over 30 cardiac cycles after single forearm contractions at 40% MVC. Sympathetic stimulation (via LBNP) blunted immediate, peak, and total hyperemic and vasodilator responses in young adults. α-Adrenergic blockade (via phentolamine) enhanced hyperemic and vasodilator responses for every cardiac cycle postcontraction in older adults. *P < 0.05 control vs. LBNP; †P < 0.05 control vs. phentolamine.
