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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Neurobiol Aging. 2011 Nov 4;33(9):2072–2081. doi: 10.1016/j.neurobiolaging.2011.09.027

Figure 2. GSPE treatment reduces the number of neurons with inclusions in the spinal cord of JNPL3 mice.

Figure 2

Spinal cord paraffin sections from ventral horns stained with a panel of antibodies against phosphorylated tau (AT8, AT100 and PHF-1), conformationally modified tau (Alz50) and human tau (HT7). Note a reduced number of phosphorylated tau-bearing neurons in the spinal cord of GSPE-treated mice as compared to untreated JNPL3 mice (see also Table 1). Six month GSPE treatment except for Alz50 (3-months).