Table 1. Tau-positive inclusions in spinal cord of JNPL3 mice.
Antibody | Number of neurons | ||
---|---|---|---|
Untreated JNPL3 mice | GSPE-treated JNPL3 mice | % Change GSPE-treated vs. untreated | |
HT7 | 7.5±1.0 | 6.0±0.2 | 80±2.7 |
Alz-50 | 7.0±0.5 | 1.0±0.5* | 38±5.4* |
AT8 | 10.0±2.0 | 1.3±0.1* | 13±1.0* |
AT100 | 6.0±2.2 | 0.6±0.2* | 10±3.3* |
PHF-1 | 12±0.5 | 4.2±0.5* | 35±4.2* |
Means ± SD
p<0.05
n=5 per group (Student's t-test)
Quantitative analysis in ventral horns.
Five sections for each antibody.