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Early combination T-cell transfer prevents tumor escape. Wild-type C57BL/6 mice (8 mice/group) were challenged subcutaneously with 5×105 B16ova cells. (A) PBS or 1×107 activated T cells were administered on day 7. Cotransfer consisted of OT-I and Pmel T cells (5×106 of each). (B) PBS or 1×107 activated T cells were administered on day 3. Data are representative of three independent experiments.
