Fig. 5.
Estimated mean (SD) for the initial response measured by Sensation Scale by genotypes of ALDH2 and GABRA2 SNP6. (A) Among subjects with ALDH2*1 /*1, there were significant differences in Anesthetic (p = 0.033) and Dynamic Peripheral (p = 0.016) subscale scores among the SNP6 TT, TC, and CC genotypes. (B) Among subjects with ALDH2*1 /*2, those with 1 or 2 copies of the SNP6 T-allele of GABRA2 showed significantly more increased initial responses in Anesthetic (p = 0.015), Dynamic Peripheral (p = 0.031), and General (p = 0.021) subscales than those homozygous for the SNP6 C-allele. Asterisks indicate significant differences (p < 0.05). An, Anesthetic subscale; DP, Dynamic Peripheral subscale; Ge, General subscale.