Table 3. Effect of CP-1, CP-2, and CP-6 on Triton WR-1339-induced hyperlipidemia in rats (Serum total Cholesterol and Triglyceride).
| Group | 0 hour | 6 hours | 24 hours | 48 hours | ||||
|---|---|---|---|---|---|---|---|---|
| Serum total Cholesterol (mg/dl) | Triglyceride (mg/dl) |
Serum total Cholesterol (mg/dl) | Triglyceride (mg/dl) |
Serum total Cholesterol (mg/dl) | Triglyceride (mg/dl) |
Serum total Cholesterol (mg/dl) |
Triglyceride (mg/dl) |
|
| G1 | 61.9±6.6 | 110.2±9.2 | 62.4±6.5 | 112.5±6.6 | 61.5±4.2 | 114.2±9.1 | 60.9±5.2 | 108.1±8.6 |
| G2 | 59.6±5.8 | 115.6±5.6 | 121.6±8.5*** | 482.4±8.6*** | 88.6±6.2*** | 394.2±10.2*** | 68.8±4.9* | 275.3±14.2*** |
| G3 | 64.5±5.7 | 108.4±5.6 | 92.2±7.5 † | 236.4±8.9 †† | 76.3±5.2 † | 186.2±7.3 †† | 67.2±5.9 | 169.4±9.8 † |
| G4 | 60.2±4.5 | 112.8±4.5 | 78.2±6.6 †† | 192.2±6.9 ††† | 68.3±4.2 †† | 172.5±8.2 ††† | 63.6±4.5 | 152.4±9.4 † |
| G5 | 58.4±5.2 | 120.2±7.6 | 96.3±8.4 † | 208.4±9.5 †† | 79.8±5.1 † | 187.1±6.2 †† | 68.8±5.1 | 171.8±8.6 † |
| G6 | 65.3±4.3 | 109.7±8.5 | 72.3±7.8 †† | 172.4±9.7 ††† | 69.3±4.8 †† | 159.6±7.9 ††† | 59.9±4.3 † | 148.7±7.6 †† |
| G7 | 59.7±3.6 | 117.9±6.5 | 86.2±4.5 † | 186.4±11.3 ††† | 72.5±4.9 †† | 171.2±8.2 ††† | 64.4±4.9 | 147.1±8.5 †† |
| G8 | 61.8±6.3 | 126.6±5.6 | 68.9±6.2 ††† | 131.4±9.3 ††† | 62.9±4.5 ††† | 128.2±6.9 ††† | 58.6±3.6 † | 122.7±8.9 ††† |
| G9 | 58.9±5.2 | 112.9±7.5 | 64.3±5.6 ††† | 122.2±8.7 ††† | 62.3±5.2 ††† | 124.9±8.1 ††† | 60.2±4.8 † | 109.4±7.8 †††† |
G1=Normal control, G2=Pathogenic control, G3=CP-1 -25 mg/kg p.o, G4=CP-1 -50 mg/kg p.o, G5=CP-2 -25 mg/kg p.o, G6=CP-2 -50 mg/kg p.o, G7= CP-6 -25 mg/kg p.o, G8=CP-6 -50 mg/kg p.o, G9=Atorvastatin -10 mg/kg p.o.
The values are expressed as Mean±SEM, (n=8).* Pathogenic control vs. Normal control (***p<0.001), † Treatments vs. Pathogenic control
(† p<0.05, †† p<0.01, ††† p<0.001).