Fig. 3.
Torso controls nucleocytoplasmic shuttling of Cic. (A) Representative FRAP data of a single bleached nucleus taken at the surface of a wild-type Drosophila embryo during early nuclear cycle 13. Quantified average intensities for the bleached nucleus (blue), immediately adjacent cytoplasm (red), a nearby nucleus (black) and cytoplasm remote from the bleached nucleus (purple). (B) Average recovery profiles of 17 bleached nuclei in the mid-body region of embryos with the torso gain-of-function allele. Error bars in B-D correspond to s.e.m. (C) Import rate constant decreases with increasing RTK signaling levels (P=0.015, based on a two-tailed t-test comparison of the means; nWT=16, ntorD4021=17). (D) Export rate constant increases with increasing RTK signaling levels (P=0.05, based on a two-tailed t-test comparison of the means; nWT=16, ntorD4021=17). Data are mean±s.e.m. in C,D.