Table 4.
Dose of corticosterone (μg/mL) |
||||
0 (n = 9) | 25 (n = 9) | 50 (n = 11) | 100 (n = 11) | |
WBC (×103/mL) | 8.7a | −5.4a | −50.3b | −44.9b |
RBC (×106/mL) | 10.2a | 8.8b | 12.8b | 9.4b |
Hemoglobin (g/dL) | 14.8a | 9.1b | 13.8b | 12.2b |
Hematocrit (%) | 52.1a | 8.8b | 11.3b | 13.7b |
Neutrophils (%) | 24.3a | −2.7a | 86.1b | 97.3b |
Lymphocytes (%) | 69.2a | 4.5a | −29.3b | −34.3b |
Monocytes (U/μL) | 566a | −51.5a,b | −63.6b | −53.7a,b |
Platelets (×103) | 1615a,b | −1.1a,b | 15.3a | −8.9b |
Values for control (0 μg/mL) group expressed as mean value for each analyte; values for treated groups (25, 50, and 100 μg/mL) expressed as % difference from control. Percentage difference = (mean treated value – mean control value)/mean control value x 100%. One-way ANOVA with post hoc Tukey multiple comparison tests were used to compare samples with control (0 μg/mL corticosterone, 1% ethanol) values. For each parameter, values with different superscript letters are significantly (P < 0.05) different from each other.