Table 2.
Molecules showing greatest upregulation or downregulation in PBMCs after MCAO compared with baseline levels (before MCAO)
Probe set ID | Gene symbol | Gene name | Fold change at 1 h | Fold change at 2 h | Fold change at 24 h |
207533_at | CCL1 | Chemokine (C-C motif) ligand 1 | 2.11 | 1.38 | 1.71 |
210133_at | CCL11 | Chemokine (C-C motif) ligand 11 | −1.49 | −1.80 | −4.04 |
216714_at | CCL13 | Chemokine (C-C motif) ligand 13 | 2.90 | 1.53 | 6.15 |
206407_s_at | CCL13 | Chemokine (C-C motif) ligand 13 | −4.86 | −4.68 | −6.50 |
210390_s_at | CCL14 | Chemokine (C-C motif) ligand 14 | −1.08 | 3.44 | −1.02 |
205392_s_at | CCL15 | Chemokine (C-C motif) ligand 15 | 2.10 | 4.74 | 2.39 |
207354_at | CCL16 | Chemokine (C-C motif) ligand 16 | 1.80 | −1.40 | 2.37 |
207900_at | CCL17 | Chemokine (C-C motif) ligand 17 | 1.17 | 3.77 | 3.16 |
209924_at | CCL18 | Chemokine (C-C motif) ligand 18 | 4.57 | 1.50 | 3.06 |
210072_at | CCL19 | Chemokine (C-C motif) ligand 19 | −4.33 | 2.64 | 1.41 |
216598_s_at | CCL2 | Chemokine (C-C motif) ligand 2 | 5.02 | −1.74 | −1.14 |
205476_at | CCL20 | Chemokine (C-C motif) ligand 20 | 1.14 | 1.44 | −1.01 |
204606_at | CCL21 | Chemokine (C-C motif) ligand 21 | 2.37 | 4.26 | 1.50 |
207861_at | CCL22 | Chemokine (C-C motif) ligand 22 | −3.53 | −10.27 | −4.75 |
210549_s_at | CCL23 | Chemokine (C-C motif) ligand 23 | −2.16 | −1.21 | −1.15 |
221463_at | CCL24 | Chemokine (C-C motif) ligand 24 | −4.75 | −2.73 | −1.69 |
206988_at | CCL25 | Chemokine (C-C motif) ligand 25 | 1.23 | −1.33 | 2.57 |
223710_at | CCL26 | Chemokine (C-C motif) ligand 26 | −2.45 | −1.72 | 2.19 |
207955_at | CCL27 | Chemokine (C-C motif) ligand 27 | 2.56 | 6.81 | 2.47 |
224027_at | CCL28 | Chemokine (C-C motif) ligand 28 | 8.40 | 8.16 | 7.60 |
205114_s_at | CCL3 | Chemokine (C-C motif) ligand 3 | 8.90 | 1.19 | 10.96 |
204103_at | CCL4 | Chemokine (C-C motif) ligand 4 | 2.51 | −1.08 | 3.05 |
204655_at | CCL5 | Chemokine (C-C motif) ligand 5 | −1.99 | −1.61 | −1.18 |
208075_s_at | CCL7 | Chemokine (C-C motif) ligand 7 | 5.40 | 5.82 | 3.62 |
214038_at | CCL8 | Chemokine (C-C motif) ligand 8 | 1.97 | 2.50 | 2.10 |
204470_at | CXCL1 | Chemokine (C-X-C motif) ligand 1 | 5.07 | 2.36 | 3.40 |
204533_at | CXCL10 | Chemokine (C-X-C motif) ligand 10 | −1.03 | −1.05 | −1.55 |
210163_at | CXCL11 | Chemokine (C-X-C motif) ligand 11 | 6.46 | 9.57 | 3.32 |
211122_s_at | CXCL11 | Chemokine (C-X-C motif) ligand 11 | 3.07 | −1.60 | 1.54 |
209687_at | CXCL12 | Chemokine (C-X-C motif) ligand 12 | −1.12 | 4.97 | −1.31 |
205242_at | CXCL13 | Chemokine (C-X-C motif) ligand 13 | 1.18 | −2.48 | −1.82 |
218002_s_at | CXCL14 | Chemokine (C-X-C motif) ligand 14 | −4.89 | −3.21 | −5.83 |
223454_at | CXCL16 | Chemokine (C-X-C motif) ligand 16 | −6.43 | −3.18 | −5.13 |
226960_at | CXCL17 | Chemokine (C-X-C motif) ligand 17 | 7.55 | −1.68 | −1.03 |
209774_x_at | CXCL2 | Chemokine (C-X-C motif) ligand 2 | 3.32 | 1.55 | 4.88 |
1569203_at | CXCL2 | Chemokine (C-X-C motif) ligand 2 | −8.74 | 1.32 | −2.22 |
207850_at | CXCL3 | Chemokine (C-X-C motif) ligand 3 | 1.96 | −1.22 | −1.30 |
215101_s_at | CXCL5 | Chemokine (C-X-C motif) ligand 5 | −2.54 | 3.28 | 2.67 |
206336_at | CXCL6 | Chemokine (C-X-C motif) ligand 6 | −3.42 | −1.91 | −3.28 |
203915_at | CXCL9 | Chemokine (C-X-C motif) ligand 9 | −6.34 | 1.16 | −2.02 |
207257_at | EPO | Erythropoietin | −19.93 | −22.40 | −3.69 |
210354_at | IFNG | Interferon γ | −1.93 | −3.83 | −1.43 |
207433_at | IL10 | Interleukin 10 | −2.24 | −2.67 | −1.71 |
206924_at | IL11 | Interleukin 11 | −1.32 | −2.11 | −1.79 |
207160_at | IL12A | Interleukin 12α | 1.71 | −6.50 | −2.75 |
207901_at | IL12B | Interleukin 12β | −1.89 | −2.47 | −2.32 |
207844_at | IL13 | Interleukin 13 | 3.00 | 1.52 | 1.70 |
205992_s_at | IL15 | Interleukin 15 | 1.05 | −1.40 | −1.17 |
217371_s_at | IL15 | Interleukin 15 | −4.55 | −2.55 | −2.79 |
209828_s_at | IL16 | Interleukin 16 | 1.06 | −2.39 | −1.24 |
216876_s_at | IL17A | Interleukin 17α | −1.46 | 4.26 | −1.75 |
220273_at | IL17B | Interleukin 17β | −6.49 | 1.46 | −1.82 |
224079_at | IL17C | Interleukin 17γ | −1.82 | −1.28 | −1.24 |
227401_at | IL17D | Interleukin 17δ | 1.08 | −1.69 | −1.00 |
234408_at | IL17F | Interleukin 17ζ | −1.54 | 3.62 | 1.12 |
206295_at | IL18 | Interleukin 18 | 4.15 | 5.21 | 6.76 |
220745_at | IL19 | Interleukin 19 | 6.68 | 1.36 | 3.50 |
210118_s_at | IL1A | Interleukin 1α | −1.98 | −2.10 | −2.75 |
205067_at | IL1B | Interleukin 1β | 2.43 | −1.01 | 2.24 |
207849_at | IL2 | Interleukin 2 | 5.81 | −1.68 | 3.42 |
224071_at | IL20 | Interleukin 20 | −1.80 | 1.32 | 1.13 |
221271_at | IL21 | Interleukin 21 | 5.64 | −1.46 | 1.35 |
222974_at | IL22 | Interleukin 22 | 2.08 | 2.79 | 1.80 |
206569_at | IL24 | Interleukin 24 | −2.44 | −3.52 | −1.78 |
220971_at | IL25 | Interleukin 25 | −1.30 | −6.94 | −3.87 |
221111_at | IL26 | Interleukin 26 | 2.36 | −2.31 | −1.18 |
1552995_at | IL27 | Interleukin 27 | 3.28 | 16.93 | 5.69 |
1552609_s_at | IL28A | Interleukin 28α | −2.53 | −7.83 | −6.97 |
1552917_at | IL29 | Interleukin 29 | −1.47 | 2.60 | 1.42 |
207906_at | IL3 | Interleukin 3 | −2.62 | −2.20 | 5.54 |
203828_s_at | IL32 | Interleukin 32 | 2.95 | 2.60 | 1.93 |
209821_at | IL33 | Interleukin 33 | −4.15 | −1.02 | −2.27 |
237046_x_at | IL34 | Interleukin 34 | 1.26 | 1.18 | −2.95 |
207538_at | IL4 | Interleukin 4 | −5.05 | −4.84 | −2.11 |
207952_at | IL5 | Interleukin 5 | 1.63 | 3.61 | 1.38 |
205207_at | IL6 | Interleukin 6 | 2.02 | −1.24 | −1.07 |
206693_at | IL7 | Interleukin 7 | 1.05 | −1.28 | −1.16 |
202859_x_at | IL8 | Interleukin 8 | 4.11 | −2.79 | 8.39 |
208193_at | IL9 | Interleukin 9 | −1.45 | 1.62 | 2.64 |
209648_x_at | SOCS5 | Suppressor of cytokine signaling 5 | −1.09 | 1.26 | 1.32 |
201107_s_at | THBS1 | Thrombospondin 1 | 18.04 | 13.65 | 21.37 |
207113_s_at | TNF | Tumor necrosis factor | 4.59 | 1.29 | 2.95 |