Figure 1.
Folate metabolic pathway. Genes included in the analysis are represented in grey circles. Abbreviations: betaine-homocysteine S-methyltransferase (BHMT), dihydrofolate reductase (DHFR), methylenetetrahydrofolate reductase (MTHFR), 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), and thymidylate synthetase (TYMS).