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. Author manuscript; available in PMC: 2012 Oct 16.
Published in final edited form as: Oncogene. 2009 Aug 24;28(43):3837–3846. doi: 10.1038/onc.2009.244

Figure 7.

Figure 7

Scheme of protein interactions. Akt is activated by convergent pathways in human cancers. ACS-1 inhibits Akt activation by increasing the activity of PP2A and not by altering EGFR or integrin signaling.