Figure 7.

Kanamycin, but not chloramphenicol, caused band-pass response with periodic treatment. (A) Microscope images of bacterial growth in the flow system. At the 8th hour, bacterial densities increased with increasing pulse periods of chloramphenicol (10 μg/ml). In contrast, bacterial densities peaked at an intermediate pulse period (120 min) of kanamycin (10 μg/ml). (B) Bacteria exhibited ‘low-pass’ response in varying pulse periods of chloramphenicol. The number of bacteria increased with increasing pulse periods. (C) Bacteria exhibited ‘band-pass’ response in varying pulse periods of kanamycin. The number of bacteria increased significantly with the pulse period of 120 min (green line). Each error bar indicates the standard deviation of five microscope images. Representative time series were obtained from two experiments. See Supplementary Figure S7 for additional data. Source data is available for this figure in the Supplementary Information.

Source data for Figure 7B ^{(53.5KB, xls)}

Source data for Figure 7C ^{(51.5KB, xls)}