Table 3. In cancer upregulated plasma membrane proteins.
| Protein names | Gene names | Uniprot | Protein abundancea | Cancer/normal ratio (fold) | P-value |
|---|---|---|---|---|---|
| Retinoic acid-induced protein 3 | GPCR5A | Q8NFJ5 | Medium | 131.0 | 0.0017 |
| Dipeptidase 1 | DPEP1 | P16444 | High | 54.0 | 0.0184 |
| Paralemmin-3 | PALM3 | A6NDB9 | Low | 22.8 | 0.0049 |
| Solute carrier family 2 (facilitated glucose transporter) | SLC2A1 | P11166 | Medium | 20.0 | 0.0045 |
| Large neutral amino acids transporter small subunit 1 | SLC7A5 | Q01650 | Medium | 17.4 | 0.0062 |
| Melanocyte-stimulating hormone receptor | MC1R | Q01726 | High | 9.6 | 0.0084 |
| Calponin-2 | CNN2 | Q99439 | High | 8.9 | 0.0090 |
| 4F2 cell-surface antigen heavy chain | SLC3A2 | P08195 | High | 7.3 | 0.0123 |
| C-terminal tensin-like protein;Tensin-4 | TNS4 | Q8IZW8 | Low | 7.2 | 0.0464 |
| Melanotransferrin | MFI2 | P08582 | Medium | 6.7 | 0.0250 |
| G protein-coupled receptor 56 | GPR56 | Q9Y653 | Low | 6.1 | 0.0305 |
| 1,2-Dihydroxy-3-keto-5-methylthiopentene dioxygenase | ADI1 | Q9BV57 | Medium | 6.0 | 0.0067 |
| Epidermal growth factor receptor kinase substrate 8 | EPS8 | Q12929 | High | 5.3 | 0.0327 |
| von Willebrand factor | VWF | P04275 | High | 5.2 | 0.0055 |
| Tyrosine-protein kinase Lyn | LYN | P07948 | Medium | 4.9 | 0.0017 |
| Exocyst complex component 4 | EXOC4 | Q96A65 | Medium | 4.8 | 0.0066 |
| Serine/threonine-protein kinase N1 | PKN1 | Q16512 | Low | 4.7 | 0.0344 |
| Protocadherin fat 1 | FAT1 | Q14517 | Medium | 4.6 | 0.0176 |
| Focal adhesion kinase 1 | PTK2 | Q05397 | Medium | 4.5 | 0.0218 |
| Neutral amino-acid transporter B(0) | SLC1A5 | Q15758 | High | 4.5 | 0.0085 |
| Junctophilin-1 | JPH1 | Q9HDC5 | Medium | 4.4 | 0.0283 |
| Syntenin-1 | SDCBP | O00560 | Medium | 4.1 | 0.0060 |
| Protein kinase C iota type | PRKCI | P41743 | Medium | 4.1 | 0.0234 |
| Rho-related GTP-binding protein RhoB | RHOB | P62745 | Medium | 4.1 | 0.0061 |
| Early endosome antigen 1 | EEA1 | Q15075 | High | 3.7 | 0.0057 |
| Amyloid β A4 protein | A4;AD1;APP | P05067 | Medium | 3.6 | 0.0123 |
| Transferrin receptor protein 1 | TFRC | P02786 | High | 3.5 | 0.0152 |
| STE20-like serine/threonine-protein kinase | SLK | Q9H2G2 | Medium | 3.5 | 0.0478 |
| Protein diaphanous homolog 1 | DIAP1 | O60610 | High | 3.5 | 0.0031 |
| Gephyrin | GPH | Q9NQX3 | Medium | 3.4 | 0.0189 |
| Lymphocyte antigen 75 | LY75 | O60449 | High | 3.4 | 0.0212 |
| Protein kinase C and casein kinase substrate in neurons 3 | PACSIN3 | Q9UKS6 | Low | 3.2 | 0.0254 |
| Periplakin | PPL | O60437 | Medium | 3.2 | 0.0488 |
| CD166 antigen | ALCAM | Q13740 | Medium | 3.1 | 0.0194 |
| Interferon-induced guanylate-binding protein 1 | GBP1 | P32455 | Medium | 3.0 | 0.0039 |
aProtein abundances assigned using MS intensities. Values correspond to the 0–25th percentile for LOW, 25th–75th percentiles for MEDIUM, and 75th–100th percentile for HIGH.