Table 4.
The proliferation inhibition activities of kansui extract and compounds 1–12 on human normal liver cells L-O2 and gastric epithelial cell GES-1 (n = 6).
| Extract/Compounds | IC50 | |
|---|---|---|
|
| ||
| L-O2 | GES-1 | |
| EtOH extract | 42.02 μg/mL | 30.67 μg/mL |
| EtOAc extract | 27.08 μg/mL | 21.89 μg/mL |
| Water extract | >100 μg/mL | >100 μg/mL |
| 1 | >100 μM | >100 μM |
| 2 | >100 μM | >100 μM |
| 3 | >100 μM | >100 μM |
| 4 | >100 μM | >100 μM |
| 5 | 12.40 μM | 8.51 μM |
| 6 | 8.22 μM | 6.67 μM |
| 7 | 13.08 μM | 3.53 μM |
| 8 | 70.78 μM | 23.51 μM |
| 9 | 34.53 μM | 22.01 μM |
| 10 | 14.36 μM | 13.44 μM |
| 11 | 17.82 μM | 8.04 μM |
| 12 | >100 μM | >100 μM |