Table 2.
Concentrations of Arg and its methylated metabolites in plasma of children and adolescents.
| Subjects | Age (Years) | ADMA (μM) | SDMA (μM) | Arg (μM) | Arg/ADMA | Method | |
|---|---|---|---|---|---|---|---|
| Wang et al. 2007 [88] | Controls | 12.6 ± 1.0 | 0.78 ± 0.16 | 0.71 ± 0.23 | 65.3 ± 21.3 | LC-MS/MS | |
| CKD | 11.3 ± 4.7 | 1.10 ± 0.35 | 2.06 ± 1.11 | 57.9 ± 22.1 | LC-MS/MS | ||
| Brooks et al. 2009 [24] | Controls | 11.3 ± 4.7 | 0.8 ± 0.2 | 0.7 ± 0.2 | 65.3 ± 21.3 | 86.8 ± 30.6 | LC-MS/MS |
| CKD | 12.6 ± 1.0 | 1.1 ± 0.3 | 2.1 ± 1.1 | 57.9 ± 22.1 | 62.4 ± 27.7 | LC-MS/MS | |
| Andrade et al. 2011 [92] | Controls | 7–18 | 0.41–0.96 | 56.4–125.4 | 83.0–218.5 | ELISA | |
| RTx | 7–18 | 0.67–1.28 | 52.6–140.3 | 55.4–177.2 | ELISA | ||
| Huemer et al. 2012 [91] | Controls | 11.6 ± 3.7 | 0.64 ± 0.66 | 59 ± 59 | 86 ± 91 | ELISA |
CKD: Chronic kidney disease; RTx: Renal transplant.