TABLE 2.
Characteristics of favourable validated case definitions
| Case definition* | Sensitivity | Specificity |
Predictive value
|
Validated sensitivity | P | |
|---|---|---|---|---|---|---|
| Positive | Negative | |||||
| 1-3-2-2 | 88.85 (88.07–90.45) | 99.58 (99.46–99.68) | 95.31 (93.71–96.14) | 98.99 (98.83–99.15) | 89.91 (89.00–90.76) | 0.255 |
| 1-3-3-2 | 86.71 (84.81–88.44) | 99.60 (99.49–99.69) | 95.14 (93.81–96.25) | 98.81 (98.62–98.97) | 86.39 (85.37–87.37) | 0.764 |
| 1-3-3-3 | 87.78 (85.95–89.45) | 99.59 (99.47–99.68) | 95.05 (93.72–96.17) | 98.90 (98.72–99.06) | 87.97 (87.00–88.89) | 0.849 |
| 1-3-3-4 | 87.99 (86.17–89.65) | 99.57 (99.45–99.66) | 94.84 (93.49–95.98) | 98.92 (98.74–99.08) | 88.59 (87.64–89.49) | 0.538 |
| 1-4-3-2 | 81.70 (79.57–83.70) | 99.78 (99.69–99.85) | 97.11 (95.99–97.99) | 98.37 (98.15–99.56) | 82.90 (81.78–83.97) | 0.300 |
| 1-4-3-3 | 83.56 (81.51–85.47) | 99.77 (99.68–99.84) | 97.01 (95.89–97.90) | 98.53 (98.33–98.71) | 85.08 (84.02–86.09) | 0.167 |
| 2-3-2-2 | 88.13 (86.32–89.78) | 99.62 (99.51–99.71) | 95.43 (94.15–96.51) | 98.93 (98.76–99.09) | 86.76 (85.74–87.72) | 0.179 |
| 2-3-2-3 | 88.92 (87.16–90.52) | 99.61 (99.50–99.70) | 95.40 (94.12–96.47) | 99.00 (99.83–99.15) | 88.31 (87.35–89.22) | 0.532 |
| 2-3-2-4 | 89.14 (87.39–90.72) | 99.59 (99.47–99.68) | 95.12 (93.81–96.22) | 99.02 (98.85–99.17) | 89.45 (88.53–90.32) | 0.734 |
| 2-4-2-2 | 83.42 (81.36–85.33) | 99.80 (99.72–99.86) | 97.41 (96.35–98.24) | 98.52 (98.32–98.70) | 83.20 (82.09–84.26) | 0.849 |
| 2-4-2-3 | 84.78 (82.78–86.62) | 99.79 (99.71–99.86) | 97.37 (96.31–98.20) | 98.64 (98.44–98.81) | 85.44 (84.40–86.45) | 0.536 |
| 2-4-2-4 | 85.28 (83.31–87.09) | 99.78 (99.69–99.85) | 97.23 (96.15–98.07) | 98.68 (98.49–98.85) | 86.97 (85.97–87.93) | 0.102 |
| 2-5-3-2 | 74.77 (72.41–77.03) | 99.90 (99.84–99.95) | 98.59 (97.68–99.21) | 97.76 (97.52–97.99) | 72.91 (71.61–74.19) | 0.169 |
| 2-5-3-3 | 77.06 (74.46–79.23) | 99.89 (99.83–99.94) | 98.54 (97.64–99.16) | 97.96 (97.73–98.18) | 76.67 (75.42–77.88) | 0.763 |
| 2-5-3-4 | 78.84 (76.61–80.96) | 99.89 (99.83–99.94) | 98.57 (97.69–99.18) | 98.12 (97.89–98.32) | 78.63 (77.42–779.80) | 0.864 |
Data presented as % (95% CI) unless otherwise indicated. Final definition indicated in bold.
*
The first digit represents the minimum number of hospitalization(s) required for an individual to be considered an inflammatory bowel disease patient. Similarly, the second and the third digits represent the minimum number of the health care contacts in physician claims and Ambulatory Care Classification System databases. The fourth digit denotes the maximum time (in years) for the definition to be fulfilled