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. 2012 Oct;26(10):729–733. doi: 10.1155/2012/852835

TABLE 1.

Current treatment recommendations for amoebic liver abscess (ALA)

Treatment phase* Drug Dose
Adult Pediatric
Initial treatment of ALA Metronidazole 750 mg PO TID × 7–10 days 35–50 mg/kg/day DIVIDED TID × 7–10 days
Tinidazole (not available in Canada) 2 g once PO daily × 3 days >3 years: 50 mg/kg/day (max 2 g) PO in 1 dose × 3 days
Clearance of luminal cysts Iodoquinol 650 mg PO TID × 20 days 30–40 mg/kg/day DIVIDED TID × 20 days (max 2 g/day)
Paromomycin 500 mg PO TID × 7 days OR
 25–35 mg/kg/day DIVIDED TID × 7 days
25–35 mg/kg/day DIVIDED TID × 7 days
*

Select one drug for the initial phase of treatment, which should then be followed by a second drug for clearance of cysts. max Maximum; PO Per oral; TID Three times daily