TABLE 1.
Treatment phase* | Drug |
Dose
|
|
---|---|---|---|
Adult | Pediatric | ||
Initial treatment of ALA | Metronidazole | 750 mg PO TID × 7–10 days | 35–50 mg/kg/day DIVIDED TID × 7–10 days |
Tinidazole (not available in Canada) | 2 g once PO daily × 3 days | >3 years: 50 mg/kg/day (max 2 g) PO in 1 dose × 3 days | |
Clearance of luminal cysts | Iodoquinol | 650 mg PO TID × 20 days | 30–40 mg/kg/day DIVIDED TID × 20 days (max 2 g/day) |
Paromomycin | 500 mg PO TID × 7 days OR 25–35 mg/kg/day DIVIDED TID × 7 days |
25–35 mg/kg/day DIVIDED TID × 7 days |
Select one drug for the initial phase of treatment, which should then be followed by a second drug for clearance of cysts. max Maximum; PO Per oral; TID Three times daily