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. 2012 Oct 3;18:2420–2437.

Table 5. Down -Regulated Genes in post HMGA2 silenced in Y79 cells (cDNA microarray analysis).

Gene classification Gene Description (Homo sapiens, gene, mRNA) Gene symbol Fold change GeneBank accession Chromosome location
Angiogenesis
Fscin homolog 1, actin-bundling protein (S .rpuratus)
FSCN1
−1.43
NM_003088
17p13.3
Apoptosis
cDNA FLJ13706 fis, clone PLACE2000317
STAMBP
−2.611
NM_201647
18q23
 
RRP5 protein homolog (Programmed cell death protein 11)
PDCD11
−1.24
NM_198490
3q21.3
Anti-apoptosis
G-2 and S-phase expressed 1
GTSE1
−1.089
NM_016426
Xp11.23
 
High-mobility group box 1
HMGB1
−1.047
NM_002128
20q13.32
Cell cycle & differentiation
Cyclin-dependent kinase 6, mRNA
CDK6
−1.55
NM_001259
14q11.2
 
CNDP dipeptidase 2 (metallopeptidase M20 family)
CNDP2
−1.084
NM_018235
9q33.3
Epithelial mesenchymal transition
Snail homolog 1 (Drosophila)
SNAI1
−1.155
NM_005985
11q13.1
 
Transcription factor 4
TCF4
−1.313
NM_003199
8q24.21
Cell proliferation
Cyclin-dependent kinase 6
CDK6
−1.55
NM_001259
12q13.3
 
Fibroblast growth factor receptor-like 1
FGFRL1
−1.822
NM_01004356
10q26.13
 
c-src tyrosine kinase
CSK
−1.14
NM_004383
14q11.2
 
Antigen identified by monoclonal antibody Ki-67
MKI67
−2.378
NM_002417
17q21.32
 
Cell division cycle 25 homolog B (S. pombe)
CDC25B
−1.319
NM_021873
1p34.1
 
E2F transcription factor 4, p107/p130-binding
E2F4
−1.354
NM_001950
8p21.1
 
Tumor protein p53 inducible protein 11
TP53I11
−1.143
NM_006034
2p13.1
Oncogene
v-abl Abelson murine leukemia viral oncogene homolog 1
ABL1
−1.167
NM_005157
22q13.2
 
RAB22A, member RAS oncogene family
RAB22A
−1.554
NM_020673
6p21.33
 
v-myc myelocytomatosis viral oncogene homolog (avian)
MYC
−1.526
NM_002467
12p13.33
 
v-crk sarcoma virus CT10oncogene homolog (avian) transcript 2
CRK
−1.775
NM_016823
1p35.1
 
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
MYBL2
−1.231
NM_002466
21q22.11
 
ELK1, member of ETS oncogene family
ELK1
−1.673
NM_005229
10q24.33
Tumor suppressors
Breakpoint cluster region, transcript variant 1
BCR
−1.428
NM_004327
22q13.31
 
Tumor protein p53 inducible nuclear protein 2
TP53INP2
−1.301
NM_021202
11q14.1
Transcription factors
Multiple endocrine neoplasia, transcript variant e1E
MEN1
−1.526
NM_130803
12q13.13
  ELK1, member of ETS oncogene family ELK1 −1.673 NM_005229 7q34