TABLE 2.

Univariate and multivariate analysis of survival

Prognostic factor	N	Locoregional control			Disease free survival			Disease specific survival			Overall survival			Colostomy free survival
		UVA		MVA	UVA		MVA	UVA		MVA	UVA		MVA	UVA		MVA
		%	p-value	p-value	%	p-value	p-value	%	p-value	p-value	%	p-value	p-value	%	p-value	p-value
T-stage
T1+2	45	80.3			80.3			92.3			75			94.4
T3+4	39	55	0.016		46.6	0.004		65.2	0.009		57.5	0.049		45.9	0.01
N-stage
N0	56	78.6			75			90.8			73.7			89.8
N+	28	50.6	0.028		47.8	0.018		59.4	0.002		56.9	0.059		71.7	0.015
Overall stage
Stage I+II	54	78.5			74.9			90.8			73.6			89.8
Stage III	30	50.8	0.031		48	0.02		59.4	0.002		56.9	0.061		71.7	0.015
PS
0	58	75.2			75.2			81.3			77.9			84.4
1+2	26	54,5			43.4			78.9			39.4	0.041		84.7
OTT
<73 days	70	73.4			69			83			72.3			70.6
≥ 73 days	14	56.3	0.043		56.3	0.062		67.5			44.2	0.062		60.9	0.086
CR
Yes	67	91.1			85.6			95.9			80			66.8
No	17	5.9	<0.001	<0.001	5.9	<0.001	<0.001	22.4	<0.001	<0.001	21	<0.001		59.3	0.014
Hb
< 120 g/l	47	58.5			52.6			68			45.5			78.7
≥ 120 g/l	37	82.7	0.016	0.061	80	0.017		94	0.015		90.7	0.001	0.007	89.6
SS
Yes	13	30.8			30.8			71.9			67.3			10.1
No	71	77.9	<0.001	0.01	73.3	<0.001	0.003	82.4			71.9			100	<0.001

N, number of patients; UVA, univariate analysis; MVA, multivariate analysis; PS, performance status; OTT, overall treatment time; CR, complete response; Hb, hemoglobin; SS, salvage surgery.