TABLE 1.

Inter-approach and inter-observer differences in HR CTV sizes

	Diff. in HR CTV [cm3] (mean (SD))	Limits of agreement (mean +/− 2SD) [cm3]	95% CI [cm3]	CCC	95% boot CI
Inter-approach analysis
Observer 1	−1.2 (2.3)	−5.8, 3.4	−8.0, 5.7	0.97	0.94, 0.99
Observer 2	1.4 (2.8)	−4.3, 7.1	−7.1, 10.0	0.96	0.88, 0.99
Inter-observer analysis
Conventional approach	2.8 (4.5)	−6.2, 11.9	−10.8, 16.4	0.87	0.75, 0.96
Test approach	0.3 (4.5)	−8.7, 9.2	−13.2, 13.7	0.91	0.84, 0.96

SD = standard deviation of differences; 95% CI = limits of 95% confidence interval for lower and upper limit; CCC = Lin’s concordance correlation coefficient; 95% boot CI = 95% bootstrap confidence interval for CCC