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. 2012 Oct 16;7(10):e47432. doi: 10.1371/journal.pone.0047432

Table 2. The effects of 2-heptanone and lidocaine on the isolated sciatic nerve of the rat.

Substance Concentration IT50 (seconds) IT0 (seconds) N
2-heptanone 10 mg/mL 22.3±1.1 195±12 7
3.41 mg/mL 39.14±4.84 221.88±7.32 12
2.28 mg/mL 108.9±0.22 358.8±18.07 4
1.41 mg/mL 109.7±2.87 517.5±25.62 4
IC50 0.469 mg/mL (SEM±0.002)
lidocaine 10.0 mg/mL 12.0±0.95 101.3±2.16 12
3.41 mg/mL 27.11±3.16 147.50±9.96 12
2.28 mg/mL 30.9±0.22 186.8±8.07 6
1.41 mg/mL 32.23±3.16 320.3±14.96 6
IC50 0.337 mg/mL (SEM±0.001).